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Symbol Name ID |
Chd7
chromodomain helicase DNA binding protein 7 MGI:2444748 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal cardiovascular system morphology |
Atrial septal defect |
Secundum atrial septal defect |
Abnormal cardiac septum morphology |
Ventricular septal defect |
Double outlet right ventricle |
Tetralogy of Fallot |
Abnormal aortic valve morphology |
Dysplastic tricuspid valve |
Right aortic arch |
Interrupted aortic arch |
Aortic arch aneurysm |
Overriding aorta |
Pulmonary artery atresia |
Patent ductus arteriosus |
Pulmonic stenosis |
Aplasia/Hypoplasia of the thymus |
| Disease(s) Associated with CHD7 | |||||||||||||||||
| CHARGE syndrome |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal pharyngeal arch artery morphology |
abnormal fourth pharyngeal arch artery morphology |
abnormal sixth pharyngeal arch artery morphology |
aortopulmonary window |
abnormal pulmonary trunk morphology |
aortic arch coarctation |
interrupted aortic arch, type b |
aorta coarctation |
abnormal common carotid artery morphology |
abnormal subclavian artery morphology |
abnormal vein morphology |
abnormal coronary vein morphology |
abnormal myocardial trabeculae morphology |
abnormal myocardium compact layer morphology |
thin ventricle myocardium compact layer |
thin myocardium |
abnormal cardiac outflow tract development |
abnormal truncus arteriosus septation |
abnormal heart development |
abnormal atrioventricular cushion morphology |
atrioventricular cushion hypoplasia |
double outlet right ventricle |
common atrioventricular valve |
double inlet heart left ventricle |
atrial septal defect |
atrioventricular septal defect |
ventricular septal defect |
thin ventricular wall |
hemorrhage |
abnormal fetal cardiomyocyte physiology |
decreased fetal cardiomyocyte proliferation |
increased cardiomyocyte apoptosis |
congestive heart failure |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi | * | ||||||||||||||||||||||||||||||||||
| Chd7Gt(RRR136)Byg/Chd7+ | |||||||||||||||||||||||||||||||||||
| Chd7Gt(XK403)Byg/Chd7+ | |||||||||||||||||||||||||||||||||||
| Chd7Whi/Chd7+ | |||||||||||||||||||||||||||||||||||
| Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi Mesp1tm2(cre)Ysa/Mesp1+ (conditional) |
* | ||||||||||||||||||||||||||||||||||
| Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi Tg(Tek-cre)1Ywa/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||
| Chd7Gt(XK403)Byg/Chd7+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Chd7Gt(XK403)Byg/Chd7+ Tg(Tbx1-cre)1Joe/0 (conditional) |
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| Chd7Gt(XK403)Byg/Chd7+ Mesp1tm2(cre)Ysa/Mesp1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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